Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0309287
PubChem CID
Molecular Formula
C11H10N2
Molecular Weight
170.215 g/mol
Synonyms/Alias
[2-Amino-6-phenylpyridine; 39774-25-9; 6-phenylpyridin-2-amine; 6-PHENYL-PYRIDIN-2-YLAMINE; CHEMBL1671950; MFCD00234719; 6-Amino-2-phenylpyridine; 2-PYRIDINAMINE; 6-PHENYL-; (Piroxicam Impurity E); 6-...
InChI Key
XDWUSBKLDNVDDQ-UHFFFAOYSA-N
InChI
InChI=1S/C11H10N2/c12-11-8-4-7-10(13-11)9-5-2-1-3-6-9/h1-8H,(H2,12,13)
IUPAC Name
6-phenylpyridin-2-amine
CAS Number
2829912-76-5

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

23 24 0 0 0 0 0 0 0 0999 V2000
-3.7970 0.5192 -0.1347 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.8950 1.5477 0.1443 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.5244 1.280...

Experimental Data

Activity Data

Target Ion Channel
Acid-sensing ion channel 3
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 763000 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.6
Holding Potential
−60 mV mV
Temperature
25–29 °C
Test Method
Patch-clamping
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
13
Rotatable Bonds
1
logP
2.3308
Complexity
54.0854
TPSA (Ų)
38.91
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
2
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